2003 – $1.2 million research grant
Research Institution : Institute for Molecular Bioscience (IMB), Brisbane, Queensland
Director of Research : Professor Alpha Yap
Feature Outcome: Purchase of two new state-of-the-art microscope systems to be housed in a purpose-built laboratory (the only one of its kind in Australia) in the Queensland Bioscience Precinct. The development represents a new level of fluorescence capability for research.
These new microscopes will enable IMB researchers to visualise the complex chemical messages cells use to ‘talk’ to each other, what causes cellular differentiation, how cells move around the body, particularly in the case of tumours, and assist in designing of anti-tumour agents.
Research Background / Overview:
The ACRF Dynamic Imaging Facility for Cancer Biology enables the pursuit of cutting-edge approaches to experimental imaging of cells, tissues and whole organisms and an integration of the IMB’s cancer research efforts, many of which directly impact on tumour biology through the understanding basic biology and in turn impact on the development of therapeutics in Australia.
Cancer involves both uncontrolled cell growth and uncontrolled movement of cancer cells in the body; so we need to understand what controls cell growth and movement normally and establish what is disturbed in disease states like cancer, to be able to develop more effective treatments, diagnostics and therapeutics.